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林俊生教授

发布时间:2020-02-25 浏览次数:


F1B8


 

个人信息:

姓名: 林俊生  

职称: 教授

电话 +86 18659913008 / +86595 22690889

邮箱: junshenglin@hqu.edu.cn / junshenglin3@hotmail.com

 

高等教育:

1994-1997 博士PhD in Biomedicine

新西兰奥克兰大学

1990-1991 工商管理毕业

澳大利亚Regent 商学院

1978-1983 医学士

福建医科大学

 

工作经历:

2012- 至今 教授、博导

华侨大学生物医学院医学院、临床医学院

2012- 至今 兼职教授、博导

新西兰维多利亚大学生物学院

2001-2012 科学家续聘为资深科学家

新西兰皇家科学院

1997-2000 博士后续聘Acadamic 研究员

新西兰奥克兰大学医学院

1991-1993  外科医师(新南威尔士州注册)

澳大利亚皇家Alfred 王子医院

1983-1989  住院续聘主治

福建医科大学附属第一医院外科

研究方向:

基于核酸分子的诊断试剂和药物开发

干细胞基础和临床研究

代血清的应用研究

强直性脊柱炎

虚拟仿真的影像处理

重组蛋白

近年发表的部分论著:

- Liu Q, Zhang W, Chen S, Zhuang Z Zhang Y Jiang , Lin J.S*, SELEX tool: a novel and convenient gel-based diffusion method for monitoring of aptamer-target binding. J Biol Eng. 2020 Jan 13;14:1. doi: 10.1186/s13036-019-0223-y. eCollection 2020. DOI: 10.1186/s13036-019-0223-y

- Guo Z.H., Zeng Y.M., Lin J.S.*. Dynamic Spatiotemporal Expression Patterns of Limbal Stem Cell Biomarkers During Mouse Development. Exp Eye Res. 2019 (in pressing)

- Guo, Z.H.; Zhang, W.; Jia, Y.Y.S.; Liu, Q.X.; Li, Z.F.; Lin, J.S*. An Insight into the Difficulties in the Discovery of Specific Biomarkers of Limbal Stem Cells. Int. J. Mol. Sci. 2018, 19(7), 1982; doi:10.3390/ijms19071982.

- Zhang W, Liu QX, Guo Z and Lin JS*, Practical Application of Aptamer-Based Biosensors in Detection of Low Molecular Weight Pollutants in Water Sources, Molecules 2018, 23(2), 344; doi:10.3390/molecules23020344

- Zhang W, Liu QX, and Lin JS*, Prevention from the Pollution of Carcinogenic Endocrine Disrupting Chemicals in Water Sources, Cancer Prevention: Current Research Journal 2017 July, 1(1):111.

- Huang X , Wang X, Xie X, Zeng S, Li Z, Xu X , Yang H, Qiu F, Lin J *, Diao Y*, Kallistatin protects against bleomycin-induced idiopathic pulmonary fibrosis by inhibiting angiogenesis and inflammation, 2017;9(3):999-1011

-  Chen Y, Lin J*, The application of aptamer in apoptosis, Biochimie 2017 Jan, 132:1-8, doi: 10.1016 /j.biochi.2016.10.008.

- Wang G, Wang X , Huang X, Yang H, Pang S, Xie X, Zeng S, Lin J*  and Diao Y*, Inhibition of integrin β3, a binding partner of kallistatin, leads to reduced viability, invasion and proliferation in NCI-H446 cells, Cancer Cell Int  (2016) 16:90

- Lin JS*, Kauff A, Diao Y, Yang HY, Lawrence S and Juengel J, Creation of DNA aptamers against recombinant BMP15, REPROD FERT DEVELOP 2016, 28(8) 1164-1171. doi: 10.1071/RD14409

- Sun A, Lin J, Chao P, et al. Biological Evaluation of Ferrocenyl Olefins: Cancer Cell Growth Inhibition, ROS Production, and Apoptosis Activity[J]. Febs Letters, 2016, 100(1):81-4.

- Huang X, Wang X, Lv Y, Xu L, Lin JS*, Diao Y*, Protection Effect of Kallistatin on Carbon Tetrachloride-Induced Liver Fibrosis in Rats via Antioxidative Stress. PLoS ONE 2014, 9 (2), e88498

- Pang SQ, Wang GQ, Jin XQ, Sun AJ, Lin JS, Diao Y, Chemical Composition of the Fatty Oil from Fructus Broussonetiae and Its Effects on Rat Plasma Lipids and Adipose Tissue, American Journal of Plant Sciences, 2016, 7, 446-452

- Sun A, Xu X, Lin J, Cui X and Xu R, Neuroprotection by Saponins, Phytotherapy Research 2015 Feb;29(2):187-200

- Wang F, Lin J, Xu R, The Molecular Mechanisms of TRAIL Resistance in Cancer Cells: Help in Designing New Drugs, Curr Pharm Des. 2014;20(42):6714-22.

- Huang KF, Huang XP, Xiao GQ, Yang HY, Lin JS*, Diao Y, Kallistatin, a novel anti-angiogenesis agent, inhibits angiogenesis via inhibition of the NF-κB signaling pathway, Biomed Pharmacother. 2014 May;68(4):455-61

- Huang KF, Yang HY, Xing YM, Lin JS *, Diao Y*, Recombinant human kallistatin inhibits angiogenesis by blocking VEGF signaling pathway, J Cell Biochem. 2014 Mar;115(3):575-84

- Pang SQ, Wang GQ, Lin JS, Diao Y, Xua RA, Cytotoxic activity of the alkaloids from Broussonetia papyrifera fruits, Pharmaceutical Biology 2014 Oct, 52(10):1315-9

- Guo, Zhi Hou and Lin, Jun Sheng *, Targeted Therapy Against BCSCs, SM Group, 2016.11.05 http://www.smgebooks.com/breast-cancer-therapy/index.php

 

国际学术杂志编委

1Editorial Board Member of SM Journal of Nephrology & Therapeutics

2Editorial Board Member of Cancer Prevention

 

近年指导学生科研的奖项

PTIM国际会议最佳Post奖(核酸生物传感器的研发)

 

A8916

 

第三届全国“梦之路杯”创意组二等奖(功能性 核酸片段的检测)

3C352


 

代血清科研项目

B5A5

 

 

 核酸适配体核心产业链金牌服务平台

 

5F56B

 




 科研转化

AE1B6