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王连会副教授

发布时间:2018-01-03 浏览次数:

王连会副教授

硕士研究生导师

地址:福建省厦门市集美区集美大道668号,华侨大学泛华科技大楼B911

邮编:361021

Emaillianhui.wang@hqu.edu.cn

研究方向:

有机合成与药物合成;有机合成方法学。

教育经历:

2010/10–2014/2 德国哥廷根大学化学学院,有机化学,博士,导师:Lutz Ackermann 教授

2007/9–2010/7 郑州大学化学系,有机化学,硕士,导师:朱志兀教授

2003/9–2007/7 郑州大学化学系,化学,学士

科研与学术工作经历:

2014/7– 华侨大学生物医学学院讲师、副教授,硕士研究生导师

主讲课程:

《有机化学》(本科生),《有机化学实验》(本科生);

《高等有机化学》(研究生),《化学药物合成》(研究生);

《化学史话》(校通识课程)。

主持科研项目:

1. 2018–2021 烯基叠氮参与的氮杂环医药分子骨架构筑(2018C073R),泉州市科技计划项目,20 万(后补助)。

2. 2017–2019 -磷叶立德双齿配体介导的 C–H 键官能团化反应研究(21602064),国家自然科学基金青年项目,20 万。

3. 2015–2018 基于过渡金属催化 C–H 键活化的氧化偶联反应研究(2015J01056),福建省自然科学基金面上项目,4 万(结题)。

4. 2015–2018可移去/修饰导向基作用下的 C–H 键功能化反应研究(JA15032),福建省中青年教师教育科研项目,2 万(结题)。

5. 2015–2019易修饰导向基作用下的直接 C–H 键活化反应研究(ZQN-PY317),中央高校基本科研业务费中青年支持计划40 万。

6. 2016–2019基于金属催化直接 C–H 键功能团化反应研究(16BS106),华侨大学科研启动基金,6 万。

入选人才计划项目:

1. 福建省高校杰出青年科研人才培育计划(2018

2. 泉州市海纳百川高端人才聚集计划(2015

主要发表文章:

20. L. Jie, L. Wang*, D. Xiong, Z. Yang, D. Zhao, X. Cui*, Synthesis of 2arylindoles through Pd(II)-catalyzed cyclization of anilines with vinyl azides. J. Org. Chem., 2018, 83, 10974−10984.

19. D. Xiong, L. Wang*, L. Jie, Z. Yang, L. Li, X. Cui*, Rhodium-catalyzed mild C7-amination of indolines with nitrosobenzenes. ChemistrySelect, 2018, 3, 13497–13500.

18. L. Wang, D. Xiong, L. Jie, C. Yu, X. Cui*, Rhodium-catalyzed oxidative homologation of N-pyrimidyl indolines with alkynes via dual CH activation: facile synthesis of benzo[g]indolines, Chin. Chem. Lett., 2018, 29, 907910.

17. L. Wang, Y. Yu, M. Yang, C. Kuai, D. Cai, J. Yu, X. Cui*, Rhodium-catalyzed synthesis of multiaryl-substituted naphthols via a removable directing group. Adv. Synth. Catal., 2017, 359, 3818−3825.

16. L. Wang, Z. Yang, M. Yang, M. Tian, C. Kuai, X. Cui*, Facile route to ortho-hydroxyanilnes through an IrIII-catalyzed direct C–H amidation of 2-phenoxypyridines. Chem. Asian J., 2017, 12, 2634–2643.

15. L. Wang, Z. Yang, M. Yang, R. Zhang, C. Kuai, X. Cui*, Iridium-catalyzed direct C–H amidation of anilines with sulfonyl azides: easy access to 1,2-diaminobenzenes. Org. Biomol. Chem., 2017, 15, 8302−8307.

14. L. Xu, L. Wang, Y. Feng, Y. Li, L. Yang, X. Cui*, Iridium(III)-catalyzed one-pot access to 1,2-disubstituted benzimidazoles starting from imidamides and sulfonyl azides. Org. Lett., 2017, 19, 4343−4346.

13. C. Kuai, L. Wang, B. Li, Z. Yang, X. Cui*, Cobalt-catalyzed selective synthesis of isoquinolines using picolinamide as a traceless directing group. Org. Lett., 2017, 19, 2102−2105.

12. C. Kuai, L. Wang, H. Cui, J. Shen, Y. Feng, X. Cui*, Efficient and selective synthesis of (E)-enamides via Ru(II)-catalyzed hydromidation of internal alkynes. ACS Catal., 2016, 6, 186190.

11. M. Wei, L. Wang, Y. Li, X. Cui*, Iridium-catalyzed direct ortho-CH amidation of benzoic acids with sulfonylazides. Chin. Chem. Lett., 2015, 26, 13361340.

10. J. Mo, L. Wang, X. Cui*, Rhodium(III)-catalyzed CH activation/alkyne annulation by weak coordination of peresters with OO bond as an internal oxidant. Org. Lett., 2015, 17, 49604963.

9. J. Mo, L. Wang, Y. Liu, X. Cui*, Transition-metal-catalyzed direct C–H functionalization under external-oxidant-free conditions. Synthesis, 2015, 47, 439459. (Invited review)

8. L. Wang, K. Rauch, A. V. Lygin, S. I. Kozhushkov, L. Ackermann*, Ruthenium-catalyzed direct oxidative alkenylation of arenes through twofold C–H bond functionalization in water: synthesis of ethyl (E)-3-(2-acetamido-4-methylphenyl)acrylate. Org. Synth., 2015, 92, 131147.

7. M. Schinkel, L. Wang, K. Bielefeld, L. Ackermann*, Ruthenium(II)-catalyzed C(sp(3))H alpha-alkylation of pyrrolidines. Org. Lett., 2014, 16, 18761879.

6. L. Wang, L. Ackermann*, Ruthenium-catalyzed ortho-CH halogenations of benzamides. Chem. Commun., 2014, 50, 10831085.

5. L. Wang, L. Ackermann*, Versatile pyrrole synthesis through ruthenium(II)-catalyzed alkene CH bond functionalization on enamines. Org. Lett., 2013, 15, 176179.

4. L. Ackermann*, L. Wang, A. V. Lygin, Ruthenium-catalyzed aerobic oxidative coupling of alkynes with 2-aryl-substituted pyrroles. Chem. Sci., 2012, 3, 177180.

3. L. Ackermann*, L. Wang, R. Wolfram, A. V. Lygin, Ruthenium-catalyzed oxidative CH alkenylations of anilides and benzamides in water. Org. Lett., 2012, 14, 728731.

2. L. Wang, X. Cui*, J. Li, Y. Wu, Z. Zhu, Y. Wu*, Synthesis of biaryls through a one-pot tandem borylation/Suzuki-Miyaura cross-coupling reaction catalyzed by a palladacycle. Eur. J. Org. Chem., 2012, 595603.

1. L. Wang, J. Li, X. Cui*, Y. Wu, Z. Zhu, Y. Wu*, Cyclopalladated ferrocenylimine as efficient catalyst for the syntheses of arylboronate esters. Adv. Synth. Catal., 2010, 352, 20022010.

授权发明专利:

2. 崔秀灵,吴养洁,王连会,李敬亚,吴豫生,朱志兀,二茂铁亚胺环钯-膦加合物在不对称联芳化合物合成中的应用,2011.7.20,中国,ZL201110022668.2

1. 吴豫生,崔秀灵,王连会,李敬亚,朱志兀,吴养洁,邹大鹏,郭瑞云,二茂铁亚胺环钯-膦加合物及其制备和应用,2010.8.18,中国,ZL201010127884.9