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张龙斌讲师

发布时间:2018-09-19 浏览次数:



张龙斌讲师

硕士生导师

邮箱:longbin_z@163.com

教育经历:

2011/09-2016/07,浙江大学,生命科学学院,微生物学专业,博士

2007/09-2011/07,福建师范大学,生命科学学院,生物技术专业,学士

科研与学术工作经历:

    2016/07-至今,华侨大学,生物医学学院,讲师

研究方向:

    非编码RNA调控,胚胎发育,神经系统发育与病变

主持或参与科研项目(课题)及人才计划项目情况:

1.      国家自然科学基金青年项目, MicroRNA对大脑皮层神经发生的反馈环路调控机制,2018/01-2020/1220万元,在研,主持;

2.      福建省自然科学基金青年项目, miR-26对神经发育的调控机制研究,2018/04-2020/044万元,在研,主持;

3.      华侨大学科研启动经费项目-引进人才类,PIWI蛋白互作非编码RNAs在大脑神经系统发育和病变过程中的遗传机制和功能分析,2017/03-2020/038万,在研,主持;

4.      国家自然科学基金面上项目,长链非编码RNA调控弄大脑皮层神经干细胞分化的分子机制,2018/01-2021/1260万元,在研,参与;

代表性研究成果:

第一作者成果:

1.      Zhang L. B., Mubarak T., Chen Y., Lee T., Pollock A., Sun T. # Counter-balance between Gli3 and miR-7 is required for proper morphogenesis and size control of the mouse brain. Front. Cellular Neurosci. 2018. 12:259.

2.      Zhang L. B., Feng M. G. # Antioxidant enzymes and their contributions to biological control potential of fungal insect pathogens. Appl. Microbiol. Biotechnol. 2018. 102: 4995-5004.

3.      Zhang H. J.*, Zhang L. B.*, Sun T. # Cohesive regulation of neural progenitor development by microRNA miR-26, its host gene Ctdsp and target gene Emx2 in the mouse embryonic cerebral cortex. Front. Mol. Neurosci. 2018. 11: 44.

4.      Zhang L. B., Tang L., Ying S. H., Feng M. G.# Two eisosome proteins play opposite roles in autophagic control and sustain cell integrity, function and pathogenicity in Beauveria bassiana. Environ Microbiol. 2017. 19:2037-2052.

5.      Zhang L. B., Tang L., Ying S. H., Feng M. G.# Distinct roles of cytoplasmic thioredoxin reductases (Trr1/Trr2) in the redox system involving cysteine synthesis and host infection of Beauveria bassiana. Appl. Microbiol. Biotechnol. 2016. 100: 10363-10374.

6.      Zhang L. B., Tang L., Ying S. H., Feng M. G.# Regulative roles of glutathione reductase and four glutaredoxins in glutathione redox, antioxidant activity, and iron homeostasis of Beauveria bassiana. Appl. Microbiol. Biotechnol. 2016. 100: 5907-5917.

7.      Zhang L. B., Tang L., Ying S. H., Feng M. G.# Subcellular localization of six thioredoxins and their antioxidant activity and contributions to biological control potential in Beauveria bassiana. Fungal Genet. Biol. 2014. 76, 1–9.

8.      Zhang H. J. *, Chang Y. F. *, Zhang L. B. *, Kim S. N., Otaegi G., Zhang Z., Nie Y. Z., Mubarak T., Li C., Qin C. F., Xu Z. H., Sun T. # Upregulation of microRNA miR-9 is associated with microcephaly and Zika virus infection in mice. Mol Neurobiol. 2018. Accepted.

主要参与成果:

9.      Du K. Z., Zhang L. B., Sun T. # m6A RNA methylation controls neural development and is involved in human diseases. Mol. Neurobiol. 2018. DOI: 10.1007/s12035-018-1138-1.

10.  Hussain G., Zhang L. B., Rasul A., Anwar H., Sohail M. U., Razzaq A., Aziz N., Shabbir A., Ali M., Sun T. # Role of plant-derived flavonoids and their mechanism in attenuation of Alzheimer’s and Parkinson’s Diseases: An update of recent data. Molecules. Doi: 10.3390/molecules23040814.

11.  Floris G., Zhang L.B., Follesa P., Sun T.# Regulatory role of circular RNAs and neurological disorders, Mol Neurobiol. 2017. 5: 5156-5165.

12.  Li F.*, Wang Z. L.*, Zhang L. B., Ying S. H., Feng M. G.# The role of three calcineurin subunits and a related transcription factor (Crz1) in conidiation, multistress tolerance and virulence in Beauveria bassiana. Appl. Microbiol. Biotechnol. 2015. 99, 827–840.

13.  Wang Z. L., Zhang L. B., Feng M. G.# Catalases play differentiated roles in the adaptation of a fungal                                                          entomopathogen to environmental stresses. Environ. Microbiol. 2013. 15, 409–418.